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Nicotine—whether from vapes, pouches, or cigarettes—can cause short-term increases in heart rate and blood pressure. These effects usually fade once nicotine leaves the body. Current evidence does not link nicotine alone to major heart problems, while long-term studies on newer products like vapes are still ongoing.
Nicotine is a stimulant. It activates the sympathetic nervous system (the “fight or flight” response) which makes the heart beat faster and blood vessels tighten.
Studies show that nicotine can cause short-lived increases in cardiovascular metrics, such as blood pressure and heart rate.1 These effects typically fade once nicotine has left the body.
How nicotine affects cardiovascular function depends on how much nicotine you get, how quickly you get it, and what other chemicals come with it. Research in this area is ongoing.
Blood pressure is how strongly blood pushes against the artery walls.2
It can change according to several factors, such as activity level and emotional step. As you get older, you are more likely to have high blood pressure.
Heart rate is how fast your heart beats. It can be affected by emotions, weight, fitness level, sleep quality, alcohol, caffeine, and some medicines.3
This article provides general information for adults who use nicotine. It is not intended as personalised medical advice. If you have heart disease, are pregnant, or are concerned about your risk, speak to your GP.
The short-term cardiovascular effects of nicotine seen in studies include:1,4
For most healthy adults, these changes usually fade once the nicotine wears off.
People who use nicotine regularly may develop tolerance, which means that increases in heart rate and blood pressure tend to be less large with chronic use.5
This does not mean that the effects disappear entirely, only that the body becomes less reactive to them.
For people with existing heart disease, the British Heart Foundation notes that:6
“Nicotine is a problem for people with heart disease. It raises the heart rate, contradicting the goal of most treatments.”
Overall, human studies on nicotine show that:1,7
The British Heart Foundation also states that nicotine is not linked to major long-term cardiovascular disease: 6
“Nicotine, while highly addictive, is not a significant health hazard for people without heart conditions. It does not cause acute cardiac events or coronary heart disease, and is not carcinogenic.”
Although nicotine’s short-term effects are temporary, researchers continue to study whether regular use with newer products (such as nicotine pouches and vapes) could influence things such as blood pressure, inflammation, blood vessels, or arterial function over time.
According to the American Heart Association, it is unclear how the short-term effects of nicotine relate to long-term cardiovascular risk.5
Nicotine affects the heart differently depending on how quickly it enters the body and what other chemicals come with it.
If nicotine enters the bloodstream quickly, this leads to faster changes in things like heart rate and blood pressure.
The table below summarises how different nicotine products compare in terms of short- and long-term cardiovascular effects.
Note that tobacco-free nicotine pouches are a relatively new product with limited research into their short- and long-term effects.
However, because they deliver nicotine in a similar way to snus, our understanding of how snus affects the cardiovascular system may also be relevant to nicotine pouches.
Table Comparing Nicotine Products and Their Cardiovascular Effects
|
Product1,4,7,8,9,10 |
Nicotine Absorption Rate |
Short-Term Effects |
Long-Term Effects |
Key Points |
|
Cigarettes |
Absorbs within seconds |
Fast spike in heart rate and blood pressure Carbon monoxide reduces oxygen delivery |
Increased risk of heart attack, stroke, heart failure, and arterial damage |
Inhalable product Contains chemicals that are harmful to the heart and blood vessels |
|
Vapes |
Slightly slower absorption rate than cigarettes |
Temporary rise in heart rate and blood pressure Some short-term effects on blood vessels |
Long-term effects unknown Long-term research on vaping and blood pressure is ongoing. |
Inhalable product Delivers nicotine without combustion |
|
Swedish snus |
Slower absorption rate than cigarettes and vapes |
Temporary rise in heart rate and blood pressure No change in arterial stiffness in short-term studies |
Mixed findings: Most Swedish snus studies show no increased risk of heart attack, heart failure, or stroke risk Others found a small increase in stroke risk compared to never smoker |
Oral product Higher pH than NRTs (higher pH means more nicotine is absorbed) International studies may show different results due to product differences |
|
Nicotine Pouches |
Slower absorption rate than cigarettes and vapes |
Possibly the same as snus |
Possibly the same as snus |
Oral product |
|
NRTs |
Slower absorption rate than cigarettes, vapes, and snus/nicotine pouches. This depends on product–patches are slower than oral NRTs) |
Moderate increase in heart rate |
No increased risk of major cardiovascular events |
Oral or transdermal product The most researched pharmaceutical product |
There is currently not enough human data to draw conclusions about the long-term effects of vaping.
This means that it is unclear if long-term vaping leads to hypertension (medically relevant high blood pressure).
The British Heart Foundation (BHF) states:6
“Experts agree that we need longer-term data on the effects of using e-cigarettes, particularly in regard to cardiovascular disease.
But since e-cigarettes have only been on sale in the UK since 2007, long-term studies don’t yet exist.”
However, based on studies of smokeless tobacco and NRTs, nicotine alone does not appear to cause the large increases in heart disease risk that are seen with combustible cigarettes.7
Nicotine activates the body’s sympathetic nervous system, which can lead to short-lived increases in heart rate and blood pressure.
These effects vary depending on how nicotine is delivered. Some products deliver nicotine more quickly, which produces a stronger cardiovascular response.
The long-term cardiovascular effects of newer nicotine products, such as vapes, require further long-term research.
Vaping can raise heart rate and may slightly raise blood pressure for a short period of time.
When it comes to vaping and blood pressure, longer-term data are needed.
If you’re wondering does nicotine raise blood pressure, the answer is yes–nicotine temporarily increases blood pressure, no matter the product or method of delivery. These changes are short-term.
Yes, nicotine activates the sympathetic nervous system, which can make the heart beat faster. This is a temporary effect which fades once the nicotine wears off.
If you’re also wondering, “Does vaping increase heart rate?”, the answer is the same–vaping causes a short-lived increase in heart rate.
According to the British Heart Foundation, nicotine is not considered a significant health hazard for people without heart conditions.
It does not cause coronary heart disease or acute cardiac events, but it is highly addictive.